“The Menlo Therapeutics leadership team we have built over the past year brings together significant dermatology and systemic therapies development experience,” Steven Basta said. “As a team, we are expanding the development program for serlopitant to treat pruritus associated with multiple conditions.”
ABOUT Serlopitant & Pruritus
Serlopitant is a once-daily oral neurokinin 1 (NK-1) receptor antagonist in development for the treatment of pruritus (itch). Pruritus is a frequent symptom of many dermatological and systemic conditions that is not adequately addressed by current therapies. Extensive scientific evidence suggests the neuropeptide, Substance P, plays a major role in the mediation of pruritus. The NK-1 receptor is the endogenous receptor for Substance P. Disrupting this common signaling pathway could address pruritus associated with a broad range of potential conditions. Menlo Therapeutics is developing serlopitant in clinical studies for the treatment of pruritus associated with several underlying medical conditions.